Pneumotox » Drug » Pravastatin

Pravastatin

2

See also under 'Statins'

Last update : 06/06/2012

I.b Pneumonitis (ILD)

1

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

1

I.aq Interstitial Pneumonitis with Autoimmune Features (IPAF)

1

V.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

1

VIII.a Angioedema (may cause UAO, asphyxia and death)

1

X.j Myopathy-Myositis-Polymyositis (see also under Xba)

1

XI.b Chest pain (acute or subacute), lone or prominent

1

Diagnosing DIRD

1

Drug and radiation history

2

Drug singularity - Correct identification of the drug

3

Consistent timing of exposure v. onset of symptoms

4

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

5

Careful exlusion of another cause

6

Remission of symptoms with removal of drug

7

Recurrence with rechallenge (rarely advisable)

8

Causality assessment

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