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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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4

VIII.a Angioedema (may cause UAO, asphyxia and death)

1
Last update : 15/05/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Atorvastatin
1
Ezetimibe
1
Fluvastatin
1
Pitavastatin
1
Pravastatin
2
Rosuvastatin
1
Simvastatin
2

Publications

Polymyalgia, hypersensitivity pneumonitis and other reactions in patients receiving HMG-CoA reductase inhibitors: a report of ten cases.
Chest 1999 Mar;115;886-9 1999 Mar

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