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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Lenalidomide

2

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

1
Last update : 28/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Pomalidomide
1
Thalidomide
2

Publications

Successful re-administration of lenalidomide after lenalidomide-induced pulmonary alveolar hemorrhage in a patient with refractory myeloma.
Annals of hematology 2015 May;94;891-2 2015 May
Lenalidomide-induced diffuse alveolar hemorrhage.
Lung India : official organ of Indian Chest Society 2014 Jan;31;90-1 2014 Jan
Pulmonary alveolar hemorrhage possibly associated with lenalidomide use.
International journal of hematology 2011 Sep;94;296-297 2011 Sep
Diffuse alveolar hemorrhage associated with lenalidomide.
International journal of hematology 2011 Jun;93;830-831 2011 Jun

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