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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Lenalidomide

2

VI.a Pulmonary embolism - Venous thrombosis/thromboembolism

1
Last update : 25/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Pomalidomide
1
Thalidomide
2

Publications

Thromboembolic events with lenalidomide-based therapy for multiple myeloma.
Cancer 2008 Apr 01;112;1522-8 2008 Apr 01
Risk of thrombosis with lenalidomide and its prevention with aspirin.
Chest 2007 Jan;131;275-7 2007 Jan
Thalidomide- and lenalidomide-associated thromboembolism among patients with cancer.
JAMA 2006 Dec 06;296;2558-60 2006 Dec 06

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