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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cisplatin

3

VI.a Pulmonary embolism - Venous thrombosis/thromboembolism

2
Last update : 16/02/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Cisplatin-Based Chemotherapy Is a Strong Risk Factor for Thromboembolic Events in Small-Cell Lung Cancer.
Cancer research and treatment 2015 Oct;47;670-5 2015 Oct

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