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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Piperacilline

1

X.a DRES syndrome - DRESS-like reaction

1
Last update : 11/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

The DRESS syndrome: the great clinical mimicker.
Pharmacotherapy 2011 Mar;31;332 2011 Mar
Use of the lymphocyte transformation test in the diagnosis of DRESS syndrome induced by ceftriaxone and piperacillin-tazobactam: two case reports.
Journal of investigational allergology & clinical immunology 2010;20;433-6 2010
Piperacillin-tazobactam-induced drug hypersensitivity syndrome.
Cutis 2006 Jun;77;353-7 2006 Jun
Hypersensitivity to piperacillin.
Allergy 1998 Aug;53;819-20 1998 Aug

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