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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Thalidomide

2

VI.b Pulmonary arterial hypertension

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Lenalidomide
2
Pomalidomide
1

Publications

[Pulmonary hypertension in a patient with talidomide].
Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 2013;37;267-9 2013
Reversible pulmonary hypertension related to thalidomide treatment for multiple myeloma.
Case reports in oncology 2011 Sep;4;487-9 2011 Sep
Pulmonary hypertension related to thalidomide therapy in refractory multiple myeloma.
Annals of oncology : official journal of the European Society for Medical Oncology 2005 Nov;16;1849-50 2005 Nov

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