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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Barbiturates

2

X.a DRES syndrome - DRESS-like reaction

1
Last update : 08/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Pentobarbital
1

Publications

DRESS in a patient taking a dietary supplement containing phenobarbital purchased over the internet.
European journal of dermatology : EJD 2008;18;209-10 2008
Drug rash with eosinophilia and systemic symptoms secondary to phenobarbitone.
Clinical neuropharmacology 2003;26;177-8 2003
[The drug hypersensitivity syndrome or DRESS syndrome to phenobarbital].
Allergie et immunologie 2001 Apr;33;173-5 2001 Apr

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