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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Vancomycin

2

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

1
Last update : 14/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Antibiotics
5

Publications

Severe anaphylaxis caused by orally administered vancomycin to a patient with Clostridium difficile infection.
Infection 2013 Apr;41;579-82 2013 Apr
Noncardiogenic pulmonary edema in a patient receiving vancomycin and oxycodone-acetaminophen.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2008 Jun;100;623-4 2008 Jun
Anaphylactic/anaphylactoid reactions during cardiac surgery.
Journal of clinical anesthesia 1989;1;426-30 1989

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