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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Valsartan

1

VIII.a Angioedema (may cause UAO, asphyxia and death)

1
Last update : 11/05/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Angiotensin II receptor blockers (ARB) - Sartans
3
Angiotensin converting enzyme inhibitors (ACEI)
5

Publications

Intraoperative angioedema induced by angiotensin II receptor blocker: a case report.
Patient safety in surgery 2018;12;27 2018
Angiotensin-converting Enzyme Inhibitor Angioedema Requiring Admission to an Intensive Care Unit.
The American journal of medicine 2015 Jul;128;785-9 2015 Jul
Side effects of angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists: are we facing a new syndrome.
The American journal of cardiology 2012 Nov 15;110;1552-3 2012 Nov 15
Valsartan-induced angioedema in a patient on angiotensin-converting enzyme inhibitor for years: case report and literature review.
American journal of therapeutics 2012 Nov;19;e189-92 2012 Nov
Angiotensin II receptor blocker-induced angioedema in the oral floor and epiglottis.
American journal of otolaryngology 2011;32;624-6 2011
[Angioedema induced by ACE inhibitors and angiotensin II-receptor antagonists: analysis of 98 cases].
Schweizerische medizinische Wochenschrift 1999 Mar 06;129;362-9 1999 Mar 06
[Regarding: Shuster C, Reinhart WH, Hartmann K, Kuhn M. Angioma induced by ACE inhibitors and angiotensin II receptor antagonists: analysis of 98 cases].
Schweizerische medizinische Wochenschrift 1999 Jul 03;129;1003-4 1999 Jul 03

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