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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Sulfasalazine

3

X.a DRES syndrome - DRESS-like reaction

1
Last update : 15/04/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Sulfamides - Sulfonamides
3

Publications

Fatal sulfasalazine-induced eosinophilic myocarditis in a patient with periodic fever syndrome.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2015;24;195-7 2015
[DRESS syndrome following sulfasalazine treatment].
Zeitschrift fur Rheumatologie 2014 Mar;73;180-3 2014 Mar
[Sulfasalazine-induced hypersensitivity syndrome associated with human herpesvirus 6 reactivation and induction of antiphospholipid syndrome].
Actas dermo-sifiliograficas 2011 Sep;102;537-40 2011 Sep
Dress syndrome with sepsis, acute respiratory distress syndrome and pneumomediastinum.
Indian journal of dermatology 2011 Nov;56;763-5 2011 Nov
DRESS-syndrome on sulfasalazine and naproxen treatment for juvenile idiopathic arthritis and reactivation of human herpevirus 6 in an 11-year-old Caucasian boy.
Journal of clinical pharmacy and therapeutics 2010 Jun;35;365-70 2010 Jun
[DRESS syndrome: 11 case reports and a literature review].
Therapie 2010;65;543-50 2010
A case of sulphasalazine-induced DRESS syndrome with delayed acute interstitial nephritis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009 Sep;24;2940-2 2009 Sep
Sulfasalazine-induced DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms).
Sao Paulo medical journal = Revista paulista de medicina 2008 Jul;126;225-6 2008 Jul

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