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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Propranolol

3

II.a Pulmonary edema, noncardiogenic (NCPE)

1
Last update : 12/09/2012
 
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Diagnosing DIRD
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Drug and radiation history
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Drug singularity - Correct identification of the drug
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Consistent timing of exposure v. onset of symptoms
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Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Beta-blockers
5

Publications

Severe hypertension, propranolol, and acute pulmonary edema.
Critical care medicine 1987 Aug;15;799-800 1987 Aug
Propranolol-induced pulmonary edema and shock in a patient with pheochromocytoma.
Archives of internal medicine 1984 Jan;144;173-4 1984 Jan
[Acute poisoning caused by beta blockers in the adult. Apropos of 7 cases].
Annales de cardiologie et d'angeiologie 1983 Jun;32;253-8 1983 Jun
Adverse reactions to propranolol in hospitalized medical patients: a report from the Boston Collaborative Drug Surveillance Program.
American heart journal 1973 Oct;86;478-84 1973 Oct

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