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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Propranolol

3

IV.f Severe or catastrophic bronchospasm or asthma attack (can be fatal)

2
Last update : 12/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Beta-blockers
5

Publications

An unusual death in an asthmatic patient.
The American journal of forensic medicine and pathology 2003 Sep;24;271-2 2003 Sep
Propranolol is contraindicated in asthma.
BMJ (Clinical research ed.) 1996 Dec 07;313;1486 1996 Dec 07
[Severe asthma attack induced by propranolol].
Duodecim; laaketieteellinen aikakauskirja 1992;108;40-2 1992
Propranolol-related bronchospasm in patients without history of asthma.
Southern medical journal 1980 Feb;73;238-40 1980 Feb

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