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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Antidepressants

3

VI.a Pulmonary embolism - Venous thrombosis/thromboembolism

1
Last update : 09/12/2018
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Clozapine
3
Olanzapine
1
Selective serotonin reuptake inhibitors (SSRI)- Serotonergic drugs
2
Tricyclic antidepressants - Tricyclic antidepressant poisoning
2

Publications

Depression, antidepressant use, and risk of venous thromboembolism: systematic review and meta-analysis of published observational evidence.
Annals of medicine 2018 Sep;50;529-537 2018 Sep

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