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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Estrogens

3

VI.a Pulmonary embolism - Venous thrombosis/thromboembolism

3
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Hormone replacement therapy
3

Publications

Venous thromboembolism in women taking hormonal contraceptives.
Expert review of cardiovascular therapy 2010 Feb;8;211-5 2010 Feb
A case of fatal pulmonary thromboembolism associated with the use of intravenous estrogen therapy.
Fertility and sterility 1999 Feb;71;373-5 1999 Feb

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