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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Angiotensin converting enzyme inhibitors (ACEI)

5

X.d Lupus - Lupus syndrome (see also Vd)

1
Last update : 28/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Alteplase (rTPA)
2
Angiotensin II receptor blockers (ARB) - Sartans
3
Benazepril
1
Captopril
4
Cilazapril
1
Enalapril
3
Fosinopril
1
Gliptins
2
Imidapril
1
Lisinopril
5
Perindopril
1
Ramipril
2
Sacubitril
1
Sitagliptin
1
Trandolapril
1

Publications

Enalapril-induced vasculitis resembling rheumatoid arthritis, lupus, sicca syndrome, and giant cell arteritis.
Revue du rhumatisme (English ed.) 1997 Jun;64;421-3 1997 Jun
Enalapril-induced antinuclear antibodies.
Lancet (London, England) 1990 Jul 21;336;187 1990 Jul 21

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