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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Minocycline

4

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

3
Last update : 13/08/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Antibiotics
5
Doxycycline
1
Minocycline (topical, transdermal)
1
Tetracycline
1

Publications

Eosinophilic pneumonia: remember topical drugs as a potential etiology.
Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 2018;44;522-524 2018
Minocycline induced eosinophilic pneumonia: case report and review of literature.
Acta clinica Belgica 2009;64;349-54 2009
Minocycline-induced acute eosinophilic pneumonia: controversial results of lymphocyte stimulation test and re-challenge test.
Internal medicine (Tokyo, Japan) 2007;46;593-5 2007
Minocycline hypersensitivity reaction with acute respiratory distress syndrome.
Intensive care medicine 2003 Feb;29;338 2003 Feb
[A case of minocycline-induced eosinophilic pneumonia presenting with multiple white eosinophilic plaques in the tracheobronchial mucosa].
Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 2001 Jan;39;24-9 2001 Jan
[Systemic reaction induced my minocycline treatment: a report of four patients and a review of the literature].
La Revue de medecine interne 1999 Oct;20;869-74 1999 Oct
Severe drug-induced pneumonitis associated with minocycline and nicotinamide therapy of a bullous pemphigoid.
Acta dermato-venereologica 1998 Sep;78;393-4 1998 Sep
A clinical study of minocycline-induced pneumonitis.
Internal medicine (Tokyo, Japan) 1996 Mar;35;176-9 1996 Mar
Minocycline-induced pneumonitis with bilateral hilar lymphadenopathy and pleural effusion.
Internal medicine (Tokyo, Japan) 1994 Mar;33;177-9 1994 Mar
Minocycline pneumonitis and eosinophilia. A report on eight patients.
Archives of internal medicine 1994 Jul 25;154;1633-40 1994 Jul 25

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