Pneumotox » Drug » Minocycline » X.s - Vasculitis, pulmonary (w/wo AH), extrapulmonary, systemic: ANCA-positive

Minocycline

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X.s Vasculitis, pulmonary (w/wo AH), extrapulmonary, systemic: ANCA-positive

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Last update : 11/10/2012

Diagnosing DIRD

1

Drug and radiation history

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Drug singularity - Correct identification of the drug

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Consistent timing of exposure v. onset of symptoms

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Clinical, imaging, BAL, pathological pattern consistent with the specific drug

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Careful exlusion of another cause

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Remission of symptoms with removal of drug

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Recurrence with rechallenge (rarely advisable)

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Causality assessment

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