Pneumotox » Drug » Mesalazine-Mesalamine-5-aminosalicylic acid-5-ASA » IV.c - Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)

Mesalazine-Mesalamine-5-aminosalicylic acid-5-ASA

In the case described (PMID 27144798), underlying ulcerative colitis, and/or shisha smoking may have played a role

Last update : 18/08/2019

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment