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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Mesalazine-Mesalamine-5-aminosalicylic acid-5-ASA

4

XI.b Chest pain (acute or subacute), lone or prominent

1
Last update : 29/08/2012
 
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Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Balsalazide
1

Publications

Chest pain in a 12-year-old girl with ulcerative colitis after therapy with mesalazine.
BMJ case reports 2013 Jun 12;2013; 2013 Jun 12
Mesalamine-induced myocarditis and coronary vasculitis in a pediatric ulcerative colitis patient: a case report.
Case reports in pediatrics 2011;2011;524364 2011
Severe chest pain in a pediatric ulcerative colitis patient after 5-aminosalicylic acid therapy.
World journal of gastroenterology 2008 Jul 21;14;4400-2 2008 Jul 21
Possible mesalamine-induced pericarditis: case report and literature review.
Pharmacotherapy 2002 Mar;22;391-4 2002 Mar
Mesalamine-induced chest pain: a case report.
The Canadian journal of cardiology 2000 May;16;667-9 2000 May
Mesalamine-associated pleural effusion with pulmonary infiltration.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 1998 Nov 01;55;2304-5 1998 Nov 01
Mesalazine toxicity.
BMJ (Clinical research ed.) 1994 Feb 19;308;533-4 1994 Feb 19

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