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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Mesalazine-Mesalamine-5-aminosalicylic acid-5-ASA

4

I.m ILD with a granulomatous component

1
Last update : 29/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Balsalazide
1

Publications

Mesalazine-induced eosinophilic variant of Wegener's granulomatosis in an ulcerative colitis patient.
Journal of Ayub Medical College, Abbottabad : JAMC 2009;21;171-3 2009
Mesalamine-induced pneumonitis during therapy for chronic inflammatory bowel disease: a pediatric case report.
Journal of pediatric gastroenterology and nutrition 2005 Oct;41;479-82 2005 Oct
Mesalamine-related lung disease: clinical, radiographic, and pathologic manifestations.
Inflammatory bowel diseases 2003 Sep;9;308-15 2003 Sep

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