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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Mesalazine-Mesalamine-5-aminosalicylic acid-5-ASA

4

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

2
Last update : 31/08/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Balsalazide
1

Publications

Eosinophilic pulmonary disease with ulcerative colitis: A case report.
Medicine 2024 Apr 26;103;e37851 2024 Apr 26
Mesalazine-induced Hypersensitivity Pneumonitis.
European journal of case reports in internal medicine 2021;8;002194 2021
Recurrent Eosinophilic Pneumonia Associated with Mesalazine Suppository in a Patient with Ulcerative Colitis.
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 2019 Apr 25;73;225-229 2019 Apr 25
Drug-induced eosinophilic pneumonia in a patient with Crohn's disease: diagnosis and treatment using fraction of exhaled nitric oxide.
Intestinal research 2017 Oct;15;529-534 2017 Oct
Mesalamine induced eosinophilic pneumonia.
Respiratory medicine case reports 2017;21;116-117 2017
Gastroenterology case report of mesalazine-induced cardiopulmonary hypersensitivity.
World journal of gastroenterology 2015 Apr 07;21;4069-77 2015 Apr 07
[Organizing pneumonia during treatment with mesalazine].
Revue des maladies respiratoires 2014 Jan;31;70-7 2014 Jan
Noninfectious interstitial lung disease during infliximab therapy: case report and literature review.
World journal of gastroenterology 2013 Aug 28;19;5377-80 2013 Aug 28
Acute eosinophilic pneumonia related to a mesalazine suppository.
Asia Pacific allergy 2013 Apr;3;136-9 2013 Apr
Mesalazine-induced eosinophilic variant of Wegener's granulomatosis in an ulcerative colitis patient.
Journal of Ayub Medical College, Abbottabad : JAMC 2009;21;171-3 2009
Mesalamine-induced unilateral eosinophilic pneumonia.
AJR. American journal of roentgenology 2001 Jul;177;257 2001 Jul
[Mesalamine-induced hypersensitivity pneumonitis].
Harefuah 1999 Jul;137;28-30, 87, 86 1999 Jul
Mesalamine-induced lung disease.
Archives of internal medicine 1997 Feb 24;157;462 1997 Feb 24
Mesalamine-induced lung toxicity.
The American journal of gastroenterology 1996 May;91;1039-40 1996 May
Mesalazine toxicity.
BMJ (Clinical research ed.) 1994 Feb 19;308;533-4 1994 Feb 19
The lung in inflammatory bowel disease.
Medicine 1993 May;72;151-83 1993 May

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