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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Mesalazine-Mesalamine-5-aminosalicylic acid-5-ASA

4

XII.c Pericardial effusion (w/wo tamponade)

1
Last update : 29/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Balsalazide
1

Publications

Gastroenterology case report of mesalazine-induced cardiopulmonary hypersensitivity.
World journal of gastroenterology 2015 Apr 07;21;4069-77 2015 Apr 07
Drug-induced pericarditis mimicking Brugada syndrome.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2007 Jan;9;66-8 2007 Jan
Possible mesalamine-induced pericarditis: case report and literature review.
Pharmacotherapy 2002 Mar;22;391-4 2002 Mar
Pleuropericarditis related to the use of mesalamine.
Digestive diseases and sciences 1996 Mar;41;624-6 1996 Mar
[Ulcerative colitis and pericarditis. The role of mesalazine hypersensitivity].
Revue medicale de la Suisse romande 1995 Nov;115;935-8 1995 Nov
[Recurrent pericarditis induced by mesalazine (5-ASA)].
Therapie 1994;49;359-61 1994

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