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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Mesalazine-Mesalamine-5-aminosalicylic acid-5-ASA
4
XII.c
Pericardial effusion (w/wo tamponade)
1
Last update :
29/08/2012
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Balsalazide
Publications
Gastroenterology case report of mesalazine-induced cardiopulmonary hypersensitivity.
Drug-induced pericarditis mimicking Brugada syndrome.
Possible mesalamine-induced pericarditis: case report and literature review.
Pleuropericarditis related to the use of mesalamine.
[Ulcerative colitis and pericarditis. The role of mesalazine hypersensitivity].
[Recurrent pericarditis induced by mesalazine (5-ASA)].