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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amitriptyline

2

X.a DRES syndrome - DRESS-like reaction

1
Last update : 06/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Amitriptylline overdose
1

Publications

Anticonvulsant hypersensitivity syndrome: cross-reactivity with tricyclic antidepressant agents.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2006 Nov;97;698-702 2006 Nov
Hypersensitivity syndrome caused by amitriptyline administration.
Postgraduate medical journal 2000 Jun;76;361-3 2000 Jun

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