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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Levofloxacin

1

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Antibiotics
5
Quinolones
3

Publications

Eosinophilic infiltrate in a patient with severe Legionella pneumonia as a levofloxacin-related complication: a case report.
Journal of medical case reports 2010 Nov 11;4;360 2010 Nov 11
[Levofloxacin-induced eosinophilic pneumonia complicated by bronchial asthma].
Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 2000 May;38;385-90 2000 May

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