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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Itraconazole

1

V.m Pleuropericarditis - Pleuropericardial effusion (ANA unknown or negative)

1
Last update : 24/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Development of pleural and pericardial effusions during itraconazole therapy of pulmonary aspergillosis.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1993 Sep;12;723-4 1993 Sep

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