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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Isoniazid - INH

2

X.d Lupus - Lupus syndrome (see also Vd)

2
Last update : 24/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

[Severe systemic lupus erythematosus induced by isoniazide].
Revue de pneumologie clinique 2009 Dec;65;361-4 2009 Dec
Drug-induced lupus syndrome. A case report implicating isoniazid.
Scottish medical journal 1967 Jul;13;245-7 1967 Jul

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