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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Combination of anticoagulant and antiplatelet drugs

1

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

1
Last update : 11/01/2019
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anticoagulants, direct oral (anti-thrombin, -IIa, -Xa) - NOAC
3
Anticoagulants, oral (vitamin K antagonists-VKA)
5
Antiplatelet (-P2Y) agents
3
Antiplatelet agents: Glycoprotein IIb/IIIa inhibitors
3
Aspirin (Salicylate-ASA) - Aspirin containing drugs
5

Publications

Pulmonary hemorrhage in a middle-aged woman as a complication of treatments for acute myocardial infarction.
Journal of cardiology cases 2010 Feb;1;e37-e41 2010 Feb

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