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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Immunoglobulins, intravenous (IVIG)

3

VI.a Pulmonary embolism - Venous thrombosis/thromboembolism

1
Last update : 08/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Hemotherapy (transfusion/infusion of whole blood, red cells, platelets, or blood products)
5

Publications

Intravenous Immunoglobulin-Induced Pulmonary Embolism: It Is Time to Act!
American journal of therapeutics 2016;23;e1074-7 2016
Severe thromboembolic complications associated with the administration of intravenous immunoglobulins.
Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 2012;36;166-7 2012
Thromboembolic complications of intravenous immunoglobulin therapy in patients with neuropathy: a two-year study.
Journal of the neurological sciences 2011 Sep 15;308;124-7 2011 Sep 15
Thromboembolic complications of intravenous immunoglobulin (IVIG) in an immunocompromised patient with Chronic Lymphocytic Leukemia: a case report.
Cases journal 2009 Nov 23;2;9078 2009 Nov 23
Deep venous thrombosis after high-dose intravenous immunoglobulin in the treatment of pemphigus vulgaris.
Cutis 2004 Jun;73;403-6 2004 Jun
Pulmonary embolism after intravenous immunoglobulin.
Journal of the Royal Society of Medicine 2001 Apr;94;187-8 2001 Apr

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