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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cyclophosphamide (i.v infusional)

2

IX.f Hiccup

1
Last update : 05/11/2019
 
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Diagnosing DIRD
1
Drug and radiation history
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Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
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Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Cyclophosphamide
4

Publications

[Hiccups ad severe hyponatremia induced by low dose cyclophosphamide therapy for Burkitt lymphoma].
Annales de biologie clinique 2011;69;613-4 2011
Hiccups and severe hyponatremia associated with high-dose cyclophosphamide in conditioning regimen for allogeneic stem cell transplantation.
American journal of hematology 2007 Jan;82;88 2007 Jan
Intractable hiccups may develop with cyclophosphamide infusion.
American journal of hematology 2004 Nov;77;319-20 2004 Nov
Hiccup--a side-effect of pulse therapy.
Dermatology (Basel, Switzerland) 1993;187;279 1993

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