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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Fentanyl analogs/derivatives/substituted

5

IX.d Respiratory failure from ventilatory depression (due to neuromuscular blockade/paralysis)

5
Last update : 21/02/2019
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Acetylfentanyl
1
Acrylfentanyl
1
Butyrfentanyl
2
Carfentanyl (carboxymethoxyfentanyl)
2
Fentanyl
5
Fentanyl (smoked, snorted, insufflated, inhaled)
2
Fentanyl (topical)
3
Remifentanil
1
Sufentanil
2

Publications

New synthetic opioid cyclopropylfentanyl together with other novel synthetic opioids in respiratory insufficient comatose patients detected by toxicological analysis.
Clinical toxicology (Philadelphia, Pa.) 2019 Sep;57;806-812 2019 Sep

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