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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Fosinopril

1

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
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Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Angiotensin II receptor blockers (ARB) - Sartans
3
Angiotensin converting enzyme inhibitors (ACEI)
5

Publications

[Hypoxic eosinophilic pneumonia in two patients treated with ACE inhibitors].
Revue des maladies respiratoires 1998 Dec;15;804-10 1998 Dec
Scleroderma and eosinophilic fasciitis in patients taking fosinopril.
The Journal of rheumatology 1997 Jun;24;1242 1997 Jun

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