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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Thrombolytic (fibrinolytic) agents

3

III.c Hemoptysis

1
Last update : 14/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Alteplase (rTPA)
2
Fibrinolytic agents (intrapleural)
1
Streptokinase
2
Tenecteplase
1
Urokinase
1

Publications

[Alveolar hemorrhage as a complication of thrombolytic therapy].
Medicina 2011;71;547-9 2011
Significance of hemoptysis following thrombolytic therapy for acute myocardial infarction.
Chest 1996 Mar;109;727-9 1996 Mar

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