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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Theophylline

3

XI.d Metabolic acidosis (incl. lactic acidosis/-gap). May cause hyperpnea/dyspnea

1
Last update : 03/05/2019
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Bezoars, pharmacobezoars, body packing
2

Publications

Theophylline toxicity: An old poisoning for a new generation of physicians.
Turkish journal of emergency medicine 2018 Mar;18;37-39 2018 Mar

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