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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Doxorubicin - Adriamycin

3

I.ad Radiation recall pneumonitis

1
Last update : 27/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anthracyclines
5
Transhepatic arterial chemoembolization (TACE)
3

Publications

"Recall" pneumonitis: adriamycin potentiation of radiation pneumonitis in two children.
Radiology 1993 May;187;465-7 1993 May
Reactivation of radiation pneumonitis by adriamycin.
The British journal of radiology 1977 Mar;50;224-7 1977 Mar

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