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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Coils (airway coil for lung volume reduction)
1
Last update :
13/05/2018
III - Pulmonary/alveolar./airway hemorrhage/bleeding
III.h
Major/massive hemoptysis
1
IV - Airway involvement
IV.k
Bronchiectasis
1
V - Pleural and/or pericardial involvement
V.f
Pneumothorax
1
XVII - Infections & related conditions
XVII.x
Aspergillus airway colonization/infection
1
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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