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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Status post-coronary artery bypass graft (CABG)
3
Last update :
15/12/2014
V - Pleural and/or pericardial involvement
V.a
Pleural effusion (uni- or bilateral) (can accompany DI-LDs)
3
V.e
Hemothorax - Serosanguineous pleural effusion
3
IX - Neuromuscular / CNS involvement - Disordered breathing during sleep
IX.j
Phrenic nerve injury - Hemi- or bilateral diaphragmatic paralysis
1
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Status post-thoracic/cardiovascular surgery
