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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Pindolol
1
See also under beta-blockers
Last update :
08/09/2012
I - Interstitial/parenchymal lung disease
I.g
Pulmonary fibrosis
1
V - Pleural and/or pericardial involvement
V.d
Pleural/pericardial effusion, ANA positive (DI lupus)
1
X - Systemic/Distant conditions, syndromes and reactions
X.d
Lupus - Lupus syndrome (see also Vd)
2
XI - Miscellaneous
XI.r
Death following exposure or poisoning
2
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Beta-blockers
