Pneumotox » Drug » Fluoxetine

Fluoxetine

2

Last update : 20/01/2012

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

1

I.b Pneumonitis (ILD)

2

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1

I.e Acute eosinophilic pneumonia (AEP)

1

I.k Lung nodule or nodules

1

I.m ILD with a granulomatous component

1

V.b Eosinophilic pleural effusion

1

VI.b Pulmonary arterial hypertension

-

VI.d Pulmonary vasculitis or capillaritis

1

XV.a Path: NSIP-cellular pattern (see also Ia, Ib)

1

XV.e Path: ILD with a granulomatous component (see also Im)

1

XV.ac Path: Pulmonary vasculitis other than capillaritis

1

Diagnosing DIRD

1

Drug and radiation history

2

Drug singularity - Correct identification of the drug

3

Consistent timing of exposure v. onset of symptoms

4

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

5

Careful exlusion of another cause

6

Remission of symptoms with removal of drug

7

Recurrence with rechallenge (rarely advisable)

8

Causality assessment

More detailed checklist