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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Drugs purchased on e-shops or on the Internet
3
Last update :
04/05/2019
I - Interstitial/parenchymal lung disease
I.a
Pneumonitis (ILD), acute and/or severe (may cause ARDS)
2
I.e
Acute eosinophilic pneumonia (AEP)
1
II - Pulmonary edema - Acute lung injury - ARDS
II.b
ARDS - Acute lung injury
2
XI - Miscellaneous
XI.r
Death following exposure or poisoning
2
XI.s
Sniffing death - Death from inhalation of compound
2
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
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Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Cathinones, synthetic ('Bath salts')
Clove cigarettes
Designer drugs
Dinitrophenol (2, 4-dinitrophenol or DNP)
Ecstasy (MDMA)
Marijuana (haschish), synthetic
Marijuana, cannabis (haschish, hash, bang, dab)