The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.a

Pulmonary edema, noncardiogenic (NCPE)

Publications

Smolarz BG, Ross J, Sachinwalla E, Marcus A, Abazia DT

Noncardiogenic pulmonary edema in a patient receiving vancomycin and oxycodone-acetaminophen.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2008 Jun;100;623-4 — 2008 Jun — 623-4

Schneir AB, Vadeboncoeur TF, Offerman SR, Barry JD, Ly BT, Williams SR, Clark RF

Massive OxyContin ingestion refractory to naloxone therapy.

Annals of emergency medicine 2002 Oct;40;425-8 — 2002 Oct — 425-8

Turturro MA, O'Toole KS

Oxycodone-induced pulmonary edema.

The American journal of emergency medicine 1991 Mar;9;201-3 — 1991 Mar — 201-3