The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LVIII.b

Path: Eosinophilic pneumonia (subacute or acute) (see also Ic)

Publications

Kang SM, Jang YR, Yoon HH, Kim S, Kim EY, Ha SY, Park JW

A Case of Balsalazide-Induced Limited Form of Granulomatosis with Polyangiitis with Bronchiolitis Obliterans Organizing Pneumonia-like Variant in Ulcerative Colitis.

Tuberculosis and respiratory diseases 2012 Mar;72;323-7 — 2012 Mar — 323-7

McGrane J, Paravasthu M, Candlish W, Gravil J

Unilateral balsalazide-induced eosinophilic pneumonia in an ulcerative colitis patient.

The journal of the Royal College of Physicians of Edinburgh 2010 Sep;40;216-8 — 2010 Sep — 216-8