The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XII.m

Cardiac- cardiorespiratory/pulmonary arrest

Publications

Jin C, Zahid E, Sherazi A, Majumder MR, Bedi P

Cardiac Arrest Due to Benzonatate Overdose.

The American journal of case reports 2019 May 03;20;640-642 — 2019 May 03 — 640-642

Yoshioka I, Surmaitis R, Katz KD

A 17-Year-Old Girl With Cough--Pulseless After Drug Overdose. Sodium benzonatate overdose.

Pediatric emergency care 2016 Mar;32;197-9 — 2016 Mar — 197-9

Cohen V, Jellinek SP, Stansfield L, Truong H, Baseluos C, Marshall JP

Cardiac arrest with residual blindness after overdose of Tessalon® (benzonatate) perles.

The Journal of emergency medicine 2011 Aug;41;166-71 — 2011 Aug — 166-71