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The Drug-Induced Respiratory Disease Website and App

Hydrocarbons (petrochemicals: petroleum, petrolatum, paraffin, vaseline, naphta, jet fuel (kerosene), Diesel, gasoil), ointments, salad oil, variegated oils, butter). Aspirated

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

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Bronchiectasis

When used orally in toddlers, oils may cause bronchiectasis later in life (PMID 7672066)

Publications

MAYOCK RL, BOZORGNIA N, ZINSSER HF

Kerosene pneumonitis treated with adrenal steroids.

Annals of internal medicine 1961 Mar;54;559-66 — 1961 Mar — 559-66

Døssing M, Khan JH

Nasal or oral oil application on infants: a possible risk factor for adult bronchiectasis.

European journal of epidemiology 1995 Apr;11;141-4 — 1995 Apr — 141-4