The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Can be near-fatal or fatal (PMID 19210362)

Publications

Wu BL, He WX, Ke M, Shang-Guan XF, He GF, Huang R

A Retrospective Analysis on 1330 Adverse Event Reports of Qingkailing in China: Further Perception of Its Risks and Rational Use.

Current medical science 2018 Dec;38;1103-1108 — 2018 Dec — 1103-1108

Zhan Q

Literature analysis of Acanthopanax anaphylactic shock in China.

Journal of traditional and complementary medicine 2015 Oct;5;253-7 — 2015 Oct — 253-7

Ji K, Chen J, Li M, Liu Z, Xia L, Wang C, Zhan Z, Wu X

Comments on serious anaphylaxis caused by nine Chinese herbal injections used to treat common colds and upper respiratory tract infections.

Regulatory toxicology and pharmacology : RTP 2009 Nov;55;134-8 — 2009 Nov — 134-8

Ji KM, Li M, Chen JJ, Zhan ZK, Liu ZG

Anaphylactic shock and lethal anaphylaxis caused by Houttuynia Cordata injection, a herbal treatment in China.

Allergy 2009 May;64;816-7 — 2009 May — 816-7