The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.b

ARDS - Acute lung injury

Publications

Ko CY, Liu PY, Chen PW

Successful management of severe acute respiratory distress syndrome caused by sodium polystyrene sulfonate aspiration: A case report.

Medicine 2019 Jul;98;e16574 — 2019 Jul — e16574

Duggal A, Salam S, Mehta A

Refractory hypoxemia due to sodium polystyrene sulfonate (kayexalate) aspiration.

Annals of the American Thoracic Society 2014 Jul;11;993-5 — 2014 Jul — 993-5