The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLVI.t

Foreign body/substance pulmonary embolism

Publications

Schilcher G, Scharnagl H, Horina JH, Ribitsch W, Rosenkranz AR, Stojakovic T, Polaschegg HD

Trisodium citrate induced protein precipitation in haemodialysis catheters might cause pulmonary embolism.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012 Jul;27;2953-7 — 2012 Jul — 2953-7

Willicombe MK, Vernon K, Davenport A

Embolic complications from central venous hemodialysis catheters used with hypertonic citrate locking solution.

American journal of kidney diseases : the official journal of the National Kidney Foundation 2010 Feb;55;348-51 — 2010 Feb — 348-51