The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Respiratory failure from ventilatory depression (due to neuromuscular blockade/paralysis)
Publications
Respiratory depression following induction of anesthesia with thiopental sodium: report of case.
Journal of oral surgery 1952 Jan;10;61-4 — 1952 Jan — 61-4
Oxygen for acute respiratory depression due to administration of thiopental sodium.
Journal of the American Medical Association 1955 Nov 12;159;1114-6 — 1955 Nov 12 — 1114-6
Time course of ventilatory depression following induction doses of propofol and thiopental.
Anesthesiology 1991 Dec;75;940-4 — 1991 Dec — 940-4