The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.b

Pneumonitis (interstitial lung disease/ILD)

Publications

Liebetrau G, Pielesch W, Tuschy U

[Pituitary gland extract insufflation lung].

Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete. 1982;37(7):218-20

Mahon WE, Scott DJ, Ansell G, Manson GL, Fraser R

Hypersensitivity to pituitary snuff with miliary shadowing in the lungs.

Thorax. 1967;22(1):13-20

Pepys J, Jenkins PA, Lachmann PJ, Mahon WE

An iatrogenic autoantibody: immunological responses to 'pituitary snuff' in patients with diabetes insipidus.

Clinical and experimental immunology. 1966;1(4):377-89

Krumhaar D, Urban M, Stempinski E, Otto H

[The so-called pituitary snuff-taker's lung. A case contribution].

Deutsche medizinische Wochenschrift (1946). 1988;113(21):857-9