The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Hypersensitivity reaction (may manifest with fever and/or skin, throat or airway involvement)
Publications
Severe paraaminosalicylic acid hypersensitivity; blood and lymph node studies.
Blood 1955 Jan;10;62-75 — 1955 Jan — 62-75
Severe reactions to paraaminosalicylic acid; a case report and brief review of literature.
Annals of internal medicine 1954 May;40;1011-6 — 1954 May — 1011-6
Allergic reaction to paraaminosalicylic acid; report of case.
Minnesota medicine 1953 Aug;36;850 — 1953 Aug — 850